Abstract
Neutrophils: Their Role in Innate and Adaptive Immunity.
Highlights
In recent years, it has become evident that neutrophils have a fundamental role in the acute phase of inflammation when they actively eliminate pathogens, and are capable of modifying the overall immune response
Neutrophils are the first leukocytes to migrate from the blood to injured or infected sites for killing pathogens and removing cellular debris
Neutrophils migrate to sites of inflammation and infection where they recognize and phagocytose invading microorganisms, in order to kill them via different cytotoxic mechanisms
Summary
It has become evident that neutrophils have a fundamental role in the acute phase of inflammation when they actively eliminate pathogens, and are capable of modifying the overall immune response. Neutrophils are the first leukocytes to migrate from the blood to injured or infected sites for killing pathogens and removing cellular debris. Neutrophils migrate to sites of inflammation and infection where they recognize and phagocytose invading microorganisms, in order to kill them via different cytotoxic mechanisms.
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