Abstract
To determine clinical and laboratory characteristics of ovarian torsion (OT; n=28) compared with a non-OT control (OC; n=64) group. Retrospective single-center review performed between January 2006 and December2016. Academic department of pediatric surgery. Postoperative diagnosis of pediatric ovarian pathology (International Classification of Diseases, 10th Revision code N83) in 88 patients who underwent 92 surgeries for suspected OT, aged from 3days to 17.8years. Predictive value for OT according to biometric, procedural, and laboratory parameters at the time of admission. Compared with OC, OT in patients aged older than 1year was associated with elevated values regarding white blood cell count, neutrophils, neutrophil to lymphocyte ratio (NLR; all P<.001), platelet to lymphocyte ratio (PLR; P=.003), platelets (P=.011), and a trend toward raised C-reactive protein (P=.054), whereas lymphocytes and lymphocyte to C-reactive protein ratio (both P<.001) were decreased. Using receiver operating characteristic analysis for differentiating OC from OT, besides lymphocytes and NLR (both area under the curve>0.9), PLR elicited strongest discriminatory accuracy (area under the curve=0.946±0.037; P<.001; sensitivity 82%; specificity 90%). At binary logistic regression analysis PLR (P=.018) was independently predictive of OT. OT was suspected on ultrasound imaging in 15/18 (83%), showed a right-sided dominance in 13/18 (72%), and was associated with younger age (P=.003). No differences regarding laboratory or procedural parameters in patients aged younger than 1year were discerned. Blood count indices such as PLR, NLR, and lymphocyte to C-reactive protein ratio might be helpful in identification of inflammatory processes as induced by ischemia in OT. Together with ultrasound and clinical features, these parameters constitute potential predictors of OT in girls aged older than 1year.
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