Neutrophil-to-Lymphocyte Ratio and Mean Platelet Volume in Predicting Coronary No-Reflow in Patients with ST Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Abstract

Abstract Background This study was designed to investigate the role of neutrophil-to- lymphocyte ratio and mean platelet volume in predicting coronary no-reflow in patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention. Objectives knows the role of neutrophil-to-lymphocyte ratio and mean platelet volume in predicting coronary no-reflow in patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention. Patients and Methods The patients were divided into 2 groups according to TIMI flow grades after primary PCI. 50 patients with TIMI flow grade 3 formed (reflow group) and 50 patients with TIMI flow grades 0-2 formed (no reflow group). Results Cases which manipulated with post stent dilatation in no reflow group were significantly higher than in the reflow group (P = 0.028). EF by M mode was significantly lower in the no reflow group cases compared to those of reflow group (P = 0.040). Absolute lymphocytes were significantly higher in the no reflow group cases compared to those of reflow group (P = 0.001). Neutrophils to lymphocytes ratio were significantly higher in the no reflow group cases compared to those of reflow group (P = 0.011). MPV was significantly higher in the no reflow group cases compared to those of reflow group (P = 0.001). Hb level was significantly higher in the no reflow group cases compared to those of reflow group (P = 0.005). Mean platelet volume and Neutrophil to lymphocyte ratio are considered a promising positive predictors of no-reflow phenomenon after primary PCI. Conclusion Mean platelet volume is considered as a promising positive predictor of no-reflow phenomenon after primary PCI. Post stent dilatation and EF by M mode are new independent factors for predicting no-reflow phenomenon in patients 1 undergoing PPCI. Neutrophils to lymphocytes ratio has a role in predicting no reflow phenomenon in patients undergoing PPCI.