Neutrophil Migration and Adhesion Molecule Expression after Acute High-Intensity Street Dance Exercise.

Leandro Borges,Renata Gorjão,Stuart Gray,Tania Cristina Pithon-Curi,Vinicius Santos,Maysa B Barros Silva,Alexandre Dermargos,Elaine Hatanaka

doi:10.1155/2018/1684013

Leandro Borges, Renata Gorjão + Show 6 more

Open Access

https://doi.org/10.1155/2018/1684013

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Abstract

The physical demands of street dancing may result in inflammation and changes in leukocyte numbers/function, impairing the health of dancers. Herein, we investigated the effect of street dancing on inflammation, adhesion molecules, and neutrophil function. Fifteen amateur dancers (mean ± SE: age 22.4 ± 1.08 years, BMI 24.8 ± 0.69 kg/m2, and body fat 12.3 ± 1.52%) participated in a single high-intensity street dance class. Blood samples were taken before and after the class. The dance class had no effect on the plasma concentration of CRP, TNF-α, IL-6, IL-10, and IL-8; however, we noted an increase in levels of IL-1β (4.06%) and sL-selectin (17.67%). The dance class resulted in a 12.36% increase in neutrophil counts, while neutrophil CD62L expression and migration were reduced (25.27% and 78.92%, resp.). After the dance class, neutrophil production of IL-8 and TNF-α increased, respectively, by 59.75% and 49.23%, in the control condition, and 43.55% and 32.22%, after LPS stimulation. A single bout of street dancing induced inflammation and reduced neutrophil migration and adhesion molecule expression. These findings may contribute to a better understanding of the susceptibility to infection after acute dance exercise.

Highlights

Hip-hop dance, a term that encompasses many styles, including popping, breakdance, funk, house, krumping, voguing, and street dance [1], has grown in popularity with an increasing number of television shows and movies and attracted a great number of followers [2]
Dancers are recognized as elite athletes and the physical demands placed on choreography and heavy performance loads can result in muscle damage and inflammation [5]
We did not find differences in the plasma concentration of C-reactive protein (CRP), TNF-α, IL-6, IL-10, and IL-8 (Table 1), the street dance class resulted in an increase in plasma IL-1β levels (4.06%, p < 0 005) (Table 1)

Summary

Introduction

Hip-hop dance, a term that encompasses many styles, including popping, breakdance, funk, house, krumping, voguing, and street dance [1], has grown in popularity with an increasing number of television shows and movies and attracted a great number of followers [2] As with other such exercises, dancing improves motor control, attention, cognition, and physical fitness, but intense training frequently leads to acute and/or chronic injury [3, 4]. After muscle damage is induced, the inflammatory response is initiated by the release of inflammatory mediators, such as proinflammatory cytokines (i.e., tumor necrosis factor-α (TNF-α) and interleukin 1β (IL-1β)) into the injured tissue [6, 7] When these events occur in an uncontrolled manner, the ensuing systemic inflammation can alter neutrophil numbers and activation status, which may lead to increased susceptibility to invasive microorganisms and may negatively affect the dancers’ performance and health. The soluble forms of sL-selectin and CD62L (bound to the membranes of leukocytes), as well as other adhesion molecules, initiate the emigration of leukocytes, by regulating the flux of rolling neutrophils and inflammatory monocytes [8], playing a critical role for the initiation of leukocyte responses [9]

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