Abstract
J. A. Gené, M. Gómez, J. M. Gutiérrez and L. Cerdas, Neutralization of hyaluronidase and indirect hemolytic activities of Costa Rican snake venoms by polyvalent antivenom. Toxicon 23, 1015–1018, 1985. — The ability of a polyvalent antivenom produced in Costa Rica to neutralize hyaluronidase and indirect hemolytic activities of Costa Rican crotalid venoms was tested. Antivenom neutralized remarkably well hyaluronidase activity of all venoms tested, with ed 50 doses ranging from 2 to 45 μl antivenom/mg venom. Neutralization of indirect hemolytic activity was also achieved using the antivenom, with ed 50 values ranging from 332 to 716μl antivenom/mg venom.
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