Neutral N, N′-bis(2-pyridinecarboxamide)-1,2-ethane as sensing material for determination of lutetium(III) ions in biological and environmental samples

Abstract

The biological properties of the lutetium as well as other lanthanide ions, primarily based on their similarity to calcium, have been the bases for research into potential therapeutic applications of lanthanide series since the early part of the twentieth century. In this research, a Lu(III) potentiometric membrane sensor based on N, N′-bis(2-pyridinecarboxamide)-1,2-ethane (PCAE) is described. The sensor exhibits a Nernstian response over a concentration range of 1.0 × 10 − 6 mol L − 1 –1.0 × 10 − 1 mol L − 1 , with a detection limit of 6.0 × 10 − 7 mol L − 1 . The best performance was achieved with a membrane composition, consisting of 30% PVC, 63% o-nitrophenyl octyl ether (NPOE), 5% PCAE and 2% sodium tetraphenylborate (NaTPB). It was found that at the pH range of 4.0–9.0, the potential response of the sensor was not affected by the pH. Furthermore, the electrode presents satisfactory reproducibility, very fast response time (5 s) and relatively good discriminating ability for Lu(III) ions with respect to many common cations and other lanthanide ions. The sensor has been applied to the determination of Lu(III) in human serum and in some soil samples where domestic devices were stored.