Neurovascular Protection in Old Age

Abstract

1. Kalaria R. Similarities between Alzheimer’s disease and vascular dementia. J Neurol Sci 2002 Nov 15;203–204: 29–34. 2. Roman GC, Sachdev P, Royall DR, et al. Vascular cognitive disorder: a new diagnostic category updating vascular cognitive impairment and vascular dementia. J Neurol Sci 2004 Nov 15;226(1–2):81–7. 4. Pohjasvaara T, Erkinjuntti T, Vataja R, et al. Comparison of stroke features and disability in daily life in patients with ischemic stroke aged 55 to 70 and 71 to 85 years. Stroke 1997 Apr;28(4):729–35. 5. Gorelick PB. William M. Feinberg Lecture: Cognitive vitality and the role of stroke and cardiovascular disease risk factors. Stroke 2005 Apr;36(4):875–9. 6. Rodgers A, Chapman N, Woodward M, et al. Perindoprilbased blood pressure lowering in individuals with cerebrovascular disease: consistency of benefits by age, sex and region. J Hypertens 2004 Mar;22(3): 653–9. 7. Birns J, Markus H, Kalra L. Blood pressure reduction for vascular risk: is there a price to be paid? Stroke 2005 Jun; 36(6):1308–13. 9. Gueyffier F, Bulpitt C, Boissel JP, et al. Antihypertensive drugs in very old people: a subgroup meta-analysis of randomised controlled trials. INDANA Group. Lancet 1999 Mar 6;353(9155):793–6. 10. Staessen JA, Gasowski J, Wang JGT, et al. Risks of untreated and treated isolated systolic hypertension in the elderly: meta-analysis of outcome trials. Lancet 2000 Mar 11;355(9207):865–72. 11. Prince MJ, Bird AS, Blizard RA, et al. Is the cognitive function of older patients affected by antihypertensive treatment? Results from 54 months of the Medical Research Council’s trial of hypertension in older adults. BMJ 1996 Mar 30;312(7034):801–5. 12. Forette F, Seux ML, Staessen JA, et al. Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial. Lancet 1998 Oct 24;352(9137):1347–51. 13. Pantoni L, Bianchi C, Beneke M, et al. The Scandinavian Multi-Infarct Dementia Trial: a double-blind, placebocontrolled trial on nimodipine in multi-infarct dementia. J Neurol Sci 2000 Apr 15;175(2):116–23. 14. Pantoni L, Rossi R, Inzitari D, et al. Efficacy and safety of nimodipine in subcortical vascular dementia: a subgroup analysis of the Scandinavian Multi-Infarct Dementia Trial. J Neurol Sci 2000 Apr 15;175(2):124–34. 15. Pantoni L, del Ser T, Soglian AG, et al. Efficacy and safety of nimodipine in subcortical vascular dementia: a randomized placebo-controlled trial. Stroke 2005 Mar; 36(3):619–24. 16. PROGRESS Collaborative group. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack. Lancet 2001 Sep 29;358(9287): 1033–41. 17. Fransen M, Anderson C, Chalmers J, et al. Effects of a perindopril-based blood pressure-lowering regimen on disability and dependency in 6105 patients with cerebrovascular disease: a randomized controlled trial. Stroke 2003 Oct;34(10):2333–8. 18. Bulpitt CJ, Beckett NS, Cooke J, et al. Results of the pilot study for the Hypertension in the Very Elderly Trial. J Hypertens 2003 Dec;21(12):2409–17. 19. Refolo LM, Malester B, LaFrancois J, et al. Hypercholesterolemia accelerates the Alzheimer’s amyloid pathology in a transgenic mouse model. Neurobiol Dis 2000 Aug; 7(4):321–31.