Neurosyphilis in the practice of clinicians: difficulties of diagnosis

Abstract

Neurosyphilis presents a complicated diagnostic task for physician’s worldwide, considering its confusing clinical presentations and long-term course, especially its latent and late forms. We present a clinical case of diagnosis of neurosyphilis, meningovascular form, with typical MRI finding and VDRL confirmation. Treatment with penicillin led to clinical improvement of psychopathological changes, whereas complete recovery was not achieved in this case. Neurosyphilis should be included into differential diagnosis of complicated cases of CNS disorder.