Neurosarcoidosis involving optic nerves and leptomeninges: computed tomography findings

Abstract

A case of neurosarcoidosis with extensive involvement of both optic nerves and intracranial leptomeninges is reported. Computed tomography demonstrates diffuse enlargement of the optic nerves and extensive nodular contrast medium enhancement of the leptomeninges of the anterior and middle cranial fossae extending into the frontal convexity. Only one such case has been previously reported in the computed tomography literature. Marked therapeutic response was obtained clinically and demonstrated on a follow-up computed tomography after therapy with corticosteroids. Differential diagnosis of computed tomography findings is discussed.