Neuropsychological profiles in mild cognitive impairment and correlation with subcortical vascular lesions in Mexican elderly: A retrospective study

Abstract

wiring FZ-F4, a clear grading from HC over MCI to AD could be found for the VSEP latencies with significant results between HC and AD (N1: p1⁄40.006, P2: p1⁄40.001) and significant results in the linear trend test (P1: p1⁄40.006, N1: p1⁄40.005, P2: p1⁄40.001), but no significant differences between HC andMCI resp. MCI and AD. In C4-F4, significant differences between AD and HC (p1⁄40.009) as well as between MCI and HC (p1⁄40.001) could be shown for P1, but no difference between the two groups of patients. As expected no potentials occurred on the left side of the head. The amplitudes of the VSEP are dispersed with no systematic link to the diagnoses of cognitive decline. Conclusions: VSEP is able to discriminate between cognitively declined patients and healthy controls with regard to the latencies of the potentials. The difference between MCI and AD reached no statistical significance, so further studies are necessary on the (diagnostic) specificity of the findings. The amplitudes of the potential have no diagnostic power.