Abstract
Materials and methods 18 women between the ages of 45–65 with a DSM-IV diagnosis of major depression were consecutively enrolled in the study at Stanford University School of Medicine, Department of Psychiatry and Behavioral Sciences. All women were treated with escitalopram in an open label design. Women were recruited from the community. All but three were Caucasian. Mean age was 55.94 and mean number of years of education was 16.36. Mood and cognition were assessed at baseline and 3-months post-treatment. Mood was assessed with the Hamilton Rating Scale for Depression (HRSD). The neuropsychological battery included the Wechsler Memory Scale-Third Edition (WMS-III), Wechsler Abbreviated Scale of Intelligence, and Trail Making Test Parts A and B.
Highlights
This study assessed mood and neuropsychological changes in a population of middle-aged depressed women treated with escitalopram
18 women between the ages of 45–65 with a DSM-IV diagnosis of major depression were consecutively enrolled in the study at Stanford University School of Medicine, Department of Psychiatry and Behavioral Sciences
All women were treated with escitalopram in an open label design
Summary
This study assessed mood and neuropsychological changes in a population of middle-aged depressed women treated with escitalopram. Neuropsychological effects of escitalopram treatment in middle-aged women Atalie Rasgon*, Laurel Zappert, Tonita Wroolie, Katherine Williams, Jennifer Keller, Stephanie Shelton, Heather Gumina and Margaret Reynolds
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