NEUROPSYCHIATRIC SYMPTOMS AND CAREGIVER BURDEN IN PARKINSON’S DISEASE DEMENTIA

Abstract

still have MMSE scores within the normal range (Figure 3). The AUC of the ACE-R in this study is low, compared with the findings in the study by Rittman T et al. This may be due to the relatively narrow difference of data collection and confidence intervals estimation in the study. Compared with the other instruments which were screened for the differential diagnosis of PD and PSP, ACE-R do not require specialized equipment or personnel and the procedure is relatively brief. It provides comprehensive coverage of neuropsychological function and can be used in numerous neurological conditions. It can be useful in assessment with elusive diagnosis. For PD-MCI, PDD and cognitive impairment of PSP, the ACE-R may offer an effective tool that could assess cognitive function. In conclusion, the ACE-R and the three subscores of the ACE-R are useful methods in supporting the differential diagnosis of PD and PSP. Importantly, ACE-R deficits are significant in terms of their effect on assessing patients’ behavior and quality of life.