Abstract
Letters and Corrections1 May 1989Neuropsychiatric HirsuitismSusan S. Braithwaite, MD, Mary Ann Emanuele, MD, Sonia Collins, MASusan S. Braithwaite, MDSearch for more papers by this author, Mary Ann Emanuele, MDSearch for more papers by this author, Sonia Collins, MASearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-110-9-748 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editor: In polycystic ovary syndrome (1) and in idiopathic hirsutism (2), the release of delta-5 steroids after administration of adrenocorticotropic hormone (ACTH) closely resembles an exaggeration of the pattern seen in normal adrenarche. In precocious adrenarche the levels of the delta-5 androgens dehydroepiandrosterone and dehydroepiandrosterone sulfate (DHEAS) are most clearly abnormal for age (3), and children who are affected have a high incidence of central nervous system dysfunction.In three adult women with neuropsychiatric disease who presented to us recently with hirsutism, the DHEAS concentrations at times equaled or exceeded 6.0 µg/mL (16.3 µM/L), a level reported by...
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
