Abstract
The P. volitans generally is an edible fish, it protein are considered to be a source of food for human and the venom use for the development of new drugs. Pharmacological character of its venom were characterised during the study period. The lionfish venom shows the neuroprotective efficacy in alcohol intoxicated albino rat brain. These findings are further confirmed by histopathological observations. Therefore, the lionfish venom could be used as a neuroprotective agent.
Highlights
In the industrial world people are having some kind of problem which may be largely man-made and iatrogenic in origin
Alcoholic liver disease (ALD) is one of the most serious results of chronic alcohol abuse in the world [3,4] have reported that the factors that mediate the occurrence of ALD are acetaldehyde, oxidative stress, hypoxia, immune response and membrane alterations
The activities of Acetyl cholinesterase (AChE) in brain was significantly (P
Summary
In the industrial world people are having some kind of problem which may be largely man-made and iatrogenic in origin. Ethanol molecule is small and soluble in both water and lipids It permeates all tissues of the body and affects most vital functions of virtually all organs including brain, liver, kidney, heart and pancreas [1]. Metabolism of alcohol leads to the generation of free radicals and the chain reaction of lipid peroxidation that causes damage to the brain and other vital organs. The oxidative stress is involved in many diseases and reactive oxygen species can be useful for immune system which might cure diseases These species still represent sources of pharmacological compounds that may be useful as research tools or lead compounds for drugs, and as such, their pharmacological actions have been the focus of recent work [8,9]. In the present study, attempts to evaluate the toxicity of lionfish P. volitans administered to rats and the incidence of oxidative stress and neurotoxicity are made
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Environmental & Analytical Toxicology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
