Abstract
partially removed for optical imaging. The exposed surface of the cortex was stained with voltagesensitive dye for 1 hour. After 10minutes of EA stimulation with low frequency/high intensity or high frequency/low intensity on Zusanli (ST36) and Yinlingquan (SP9), optical signals were recorded from the primary somatosensory (SI) cerebral cortexusingoptical imaging. Results: The displayed cortex images showed propagated and amplified neural activities in the SI cortex area after electrical stimulation of the peripheral receptive field of nerve-injured rats. After EA stimulation with either low frequency/high intensity or high frequency/low intensity, optical signals and the area of activation in the SI cortex decreased substantially and were followed by time-dependent recovery. Conclusion: This study provides solid evidence that EA stimulation with low frequency/high intensity or high frequency/low intensity has similar inhibitory effects on the excited neuronal signaling caused by painful stimuli. This research was supported by the Basic Science Research Program through the National Research Foundation (NRF) funded by the Ministry of Science, ICT & Future Planning (No. 2014R1A2A2A04004407). Contact: Bae Hwan Lee, bhlee@yuhs.ac
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