Neurophysiological study of normal pressure hydrocephalus.

Abstract

A neuropsychological Mental Deterioration Battery (MDB) was used to identify deterioration profiles of 43 patients afflicted with normal pressure hydrocephalus (NPH) (n = 18) or other forms of dementia (n = 25). The NPH patients submitted to a shunt-intervention (n = 10) were also evaluated after surgery. A comparison of profiles, obtained from the experimental and control groups, shows that NPH patients seem to be more impaired in tests designed to detect frontal lobe involvement. Some implications of the relatively greater impairment of frontal functions in NPH dementia are discussed.