Abstract
To investigate methanol extracts of various parts of Rubus fruticosus L. (Rosaceae) for various neuropharmacological activities, such as anxiolytic, muscle relaxant, antidepressant, and sedative activities. The extracts were administered to albino mice orally at doses of 100, 300, and 500 mg/kg. The antidepressant activity was determined by using the forced swimming test, while line crossing in a special box was used for assessment of locomotor activity. All extracts were found to be anxiolytic in nature, while no muscle relaxing activity or sedative effect was observed. The order of central nervous system (CNS) depressant effect for various parts of R.fruticosus was fruit > root > leaves > stem. Our results indicate that methanolic extract of various parts of R. fruticosus possess anxiolytic and CNS depressant effects but do not possess significant sedative or muscle relaxing potential.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
