Abstract
Microinjection of neuropeptide Y (NPY) into the suprachiasmatic region of the hypothalamus (SCN) phase shifted the circadian activity rhythm of hamsters housed in constant light. NPY advanced the phase when injected during the 12 h that preceded the daily onset of activity and tended to phase delay the activity cycle when injected during the 12 h after activity onset. In contrast, injection of saline into the SCN or NPY into the ventricular system had no effect on circadian phase. These and other data suggest that NPY functions as a chemical messenger important for the light-dark cycle entrainment of circadian rhythms.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.