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Abstract
AbstractNeuropeptide Y (NPY) has a broad distribution and numerous physiological functions in the peripheral and central nervous systems. The gene transcription and fundamentals of peptide processing have been elucidated. NPY levels and release are exquisitely sensitive to pharmacological and physiological manipulation. NPY receptors have been partially characterized pharmacologically. The effects of NPY on target organs and their implications for drugs interacting with the NPY system are described.
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