Abstract
The neuropathological effects of local injection of tetanus toxin (TT) into various structures of the brain were studied in experiments on rats. Definite neuropathological changes were observed in the animals, different from those found after injection of TT elsewhere. As a rule the action of TT in a given region of the brain was local. The experiments confirm the theory of generator mechanisms of neuropathological syndromes, according to which specific manifestations of the corresponding syndrome are determined by the location of a generator of pathologically enhanced excitation in a certain brain structure.
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