Neurons of the ipsilateral and contralateral sensorimotor cortices in the cat: Their responses related to a conditioned reflex movement by one extremity

Abstract

The activity of sensorimotor cortex neurons related to the performance of conditioned reflex movements by one extremity, which were evoked by the application of distant stimuli, was recorded in chronic experiments on cats. In the course of an experiment, the reflex performance was transferred from one extremity to the another, and, thus, the neuronal responses were studied in two situations: in the ipsilateral or in the contralateral position of a neuron with respect to the operating extremity. According to the pattern of their responses to the conditioning stimulus (CS), the neurons were classified into three groups. The first group consisted of neurons with bilateral type of responses, generating similar responses in both positions. The cells responding to the CS only in the “ipsilateral situation” formed the second group. The third group consisted of neurons with reciprocal responses, in the two above positions. The results obtained in our study illustrate basic regularities in the functioning of ipsilateral and contralateral hemispheres within the behavioral model used, and show that both hemispheres actively participate in the course of a preparation for the unilateral conditioned movement performance.