Abstract
Energy homeostasis at the organismal level requires signaling between different cell types, tissues, and organs to coordinate energy uptake and expenditure. The larval stage of Drosophila development provides a powerful model to study the mechanisms at play. Among the various sources of signals that control fat storage in the fat body, the brain has been studied primarily as a regulator of relevant behaviors such as feeding and exercise. Here, I briefly review what is known about a brain-fat-body axis for communication in the context of energy homeostasis in Drosophila larvae and introduce a protocol for rapidly identifying changes in body fat resulting from manipulation of gene or neuronal function.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
