Neuronal mechanisms of the interaction of Deiters' nucleus with some brainstem structures

Abstract

The effects of stimulation of the interstitial nucleus of Ramón y Cajal, as well as the nucleus of Darkschewitsch, inferior olive and nucleus reticularis tegmenti pontis on the neuronal activity of the lateral vestibular nucleus of Deiters were studied by means of an intracellular recording technique. Stimulation of these structures is shown to lead to antidromic and orthodromic activation of Deiters' neurons. Collaterals of vestibulospinal neurons entering these structures are revealed electro-physiologically. It was shown that stimulation of the rostral part of the inferior olive evoked in Deiters' neurons predominantly antidromic responses, whereas stimulation of the caudal part of the inferior olive leads mostly to synaptic activation. Stimulation of Ramón y Cajal's and Darkschewitsch's nuclei evokes mono- and/or polysynaptic excitatory and inhibitory postsynaptic potentials in Deiters' neurons. Mono-, oligo- and/or polysynaptic inhibitory postsynaptic potentials were also evoked by stimulation of nucleus reticularis tegmenti pontis, as well as the rostral and, particularly, caudal parts of the inferior olive. Stimulation of the caudal part of the inferior olive evoked mono-, oligo- and/or polysynaptic excitatory postsynaptic potentials in Deiters' neurons. Convergence of influences from the stimulated structures on the vestibular neurons under study was shown. A topical correlation between Deiters' nucleus and the brainstem nuclei mentioned above was found. The presence of inhibitory and excitatory interaction of these structures with Deiters' nucleus was established.