Abstract
How do nerve cells regulate the level of free calcium ions in their cytoplasm? It appears that low resting levels must be maintained while changes sufficient to activate many intracellular processes must also be allowed. This article briefly explores some of the cellular mechanisms that could contribute to calcium homeostasis in neurones. If we are to conclude anything, it is that the regulation of cell calcium is a highly complex task, and understanding the process will certainly yield new insights into the normal physiology and the pathology of nerve cells.
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