Abstract
Neuromodulation for Lower Urinary Tract Dysfunction – An Update
Highlights
Sacral neuromodulation has been available as a treatment option for patients with lower urinary tract disorders for more than a decade (Table 1)
As in the study by Fowler et al.[4], no direct motor response was observed. These findings indicate that spinal pathways may well be involved in producing the anal and pelvic floor response to S3 stimulation since the spinal cord injury will have interrupted the spino-bulbo-spinal pathways
The impact that a treatment might have when introduced into clinical practice is better gauged by a number needed to treat analysis
Summary
Sacral neuromodulation has been available as a treatment option for patients with lower urinary tract disorders for more than a decade (Table 1). More than 25,000 patients have received InterStim® therapy worldwide for urge incontinence, frequency/urgency, urinary retention in women, chronic constipation, and faecal incontinence[1]. A number of prospective trials and numerous case series have provided an evidence base that has confirmed the efficacy and durability of the treatment[2]. Substantial gaps in our knowledge remain and this review will look at some of the questions that have been raised during the first 14 years of clinical experience with sacral nerve stimulation in the management of lower urinary tract disorders
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
