Abstract

This review examines the neurologic complications of several rheumatic diseases, including rheumatoid arthritis, seronegative spondyloarthritis, systemic lupus erythematosus, scleroderma and related diseases, vasculitis, spinal osteoarthritis and spondylosis, and primary Sjögren syndrome. Tables describe the categories of neurologic complications of lupus, the prevalence of neurologic manifestations among patients with lupus, distribution of nerve involvement among patients with mononeuritis multiplex caused by microscopic polyangiitis, sensitivity of combined superficial peroneal nerve and peroneus brevis muscle in patients with suspected vasculitis, sites of central nervous system involvement among patients with parenchymal neuro-Behçet syndrome, and localization of cervical radiculopathy. Figures include a radiograph of a patient with rheumatoid arthritis, magnetic resonance imaging showing diffuse pachymeningeal enhancement and the cervical patient with lupus, and photographs of a muscle biopsy of a patient with vasculitis nephropathy and anterior ischemic optic neuropathy secondary to temporal arteritis. This review contains 5 figures, 6 tables, and 77 references Keywords: Rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, scleroderma, vasculitis, spinal osteoarthritis, spondylosis, Sjögren syndrome, neurologic deficit, radiculopathy, Sciatica

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