Abstract

Phantom limb pain as a manifestation of paclitaxel neurotoxicity. (Providence Hospital, Southfield, MI) Mayo Clin Proc 2000;75:740–742.This case report described 2 patients with prior amputation who experienced phantom limb pain (PLP) after receiving paclitaxel therapy. A third patient experienced disabling neurotoxicity in the extremity of a prior ulnar nerve and tendon transposition after receiving paclitaxel. This unique syndrome should be identified as a direct causal effect of paclitaxel. The pathophysiology of PLP and the treatment options are reviewed. Conclude that physicians should be aware that PLP can occur after initiation of paclitaxel.

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