Neurological Manifestations of Patients Hospitalized with Coronavirus Disease 2019 in Babol, Iran

Abstract

Background: The coronavirus disease 2019 (COVID-19) has been associated with a wide range of clinical symptoms. Objectives: The present study aims to investigate the neurological manifestations among patients hospitalized with COVID-19 in Rouhani Hospital in Babol. Methods: This is a descriptive cross-sectional survey conducted in March and April 2020 on patients admitted to Rouhani Hospital in Babol with COVID-19. A number of 230 medical records were selected randomly from a list. The data were collected using the demographic characteristics questionnaire and a checklist for the neurological symptoms. Results: Among the 230 patients with COVID-19 (mean [SD] age, 59.85 [16.22] years; 138 men [60%]), 127 (56%) patients had at least one neurologic symptom. The most common symptoms of the central nervous system disorder were headache (34%), dizziness (25%), and impaired consciousness (20%), and the most prevalent symptoms of the peripheral nervous system disorder were taste impairment (17%) and smell impairment (16%). The occurrence of transient ischemic attack (TIA) in women was significantly higher than in men (P = 0.02). Moreover, the incidence of dizziness, impaired consciousness, ataxia, cerebrovascular accident (CVA), anorexia, and smell impairment had a significant relationship with age (P < 0.05). Conclusions: The neurological manifestations are prevalent and substantial among patients with COVID-19. Therefore, it is suggested that the healthcare workers take these symptoms seriously, especially in the outbreak of COVID-19, and take the pertinent preventive and protective measures.