Abstract

Neurological manifestations in COVID-19 caused by SARS-CoV-2.

Highlights

  • The recent outbreak of COVID-19 caused by SARS-CoV-2 coronavirus has turned the world into chaos with its ominously high rate of transmissions

  • The prognostic and diagnostic significance of neurological sign and symptoms in COVID-19 patients can be gauged by fact that the protocol designed to investigate the First Few X cases (FFX) and their close contacts by the World Health Organization (WHO), includes a separate section for “other neurological signs” in addition to separate columns for respiratory symptoms.[3]

  • The hematogenous route appears to be the likely pathway for SARS-CoV-2 to reach the brain, but other routes to the CNS like across the cribriform plate (Figure 1B) of the ethmoid bone in proximity to the olfactory bulb[7] should be taken into consideration in cases of early-phase COVID-19-affected patients who exhibit loss of smell and taste accompanied with neurological signs and symptoms

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Summary

Introduction

The recent outbreak of COVID-19 caused by SARS-CoV-2 coronavirus has turned the world into chaos with its ominously high rate of transmissions. The prognostic and diagnostic significance of neurological sign and symptoms in COVID-19 patients can be gauged by fact that the protocol designed to investigate the First Few X cases (FFX) and their close contacts by the World Health Organization (WHO), includes a separate section for “other neurological signs” in addition to separate columns for respiratory symptoms.[3] reports of COVID-19-affected individuals experiencing convulsions in prevalent areas is alarming and need to be distinguished from febrile convolution that is expected to occur with high-grade fever in patients with COVID-19.

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