Abstract
<h3>Objective:</h3> To describe the neurological complications in COVID-19 survivors 3 months after hospital discharge <h3>Background:</h3> Since the beginning of the pandemic in 2019 of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing human coronavirus disease 2019 (COVID-19) persistent symptoms are being reported among COVID-19 survivors, our objective is to report neurological manifestations in hospitalized COVID-19 survivors. <h3>Design/Methods:</h3> We report the neurological sequelae observed in a cohort of 238 patients who were admitted in a single center with acute respiratory distress syndrome (ARDS) due to COVID-19, 3 months after their hospital discharge, a complete neurological examination and MOCA cognitive screening test was performed by 2 neurologists in Mexico City from August 31, 2020 to January 8, 2021. <h3>Results:</h3> In all patients, reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assays of nasopharyngeal samples were positive for SARSCoV-2. The mean age of the patients was 51 years, 97 patients (68.3%) needed mechanical ventilatory support, 52% with a periphery oxygen saturation at admission of less than 60%, 10.6% were health care workers, 8 patients has had previous neurologic disorders. The main sequels observed were sensory motor neuropathy (66.4%), myopathic pain (43. 9%), cognitive complains (59.7%) with an average MOCA of 25.5 (46.6%). 5 patients had ischemic cerebral vascular disease, 5 patients had seizures, 108 (45.6%) affective symptoms, 52.2% patients with a RANKIN less than 2. <h3>Conclusions:</h3> It is crucial a multidisciplinary long term follow up of the patients who survived the COVID-19 to recognize the different range of neurological sequelae; this in order to provide better clinical prognoses and to optimize the algorithms of treatment <b>Disclosure:</b> Dr. Santos has nothing to disclose. Dr. Rodríguez has nothing to disclose. Dr. Lopez Gonzalez has nothing to disclose.
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