Neurological Manifestations among Patients with HIV – Active Tuberculosis co Infection

Mohamed A Taha,Razeen A Alsherif,Abbashar M Hussein,Khabab Abbasher,Amira Sidig,Mohammed I Alfaki,Musaab M Alfaki,Osman B M O Arbb,Khalid Hajnoor,Ahmed S Yeddi,Mohamed A Alnor,Mohammed A Kabeer,Mohamed A Abdelrahim

doi:10.34257/gjmravol20is2pg25

Abstract

At least one-third of the 35.3 million people living with HIV worldwide are infected with latent tuberculosis. Tuberculosis is the most common presenting illness among people living with HIV, including those who are taking antiretroviral treatment. There were an estimated 1.1 million HIV positive new TB cases globally in 2012. Around 75% of these people live in sub-Saharan Africa. Despite its great burden, neurological manifestations have not been described yet in patients with HIV-active tuberculosis, although tuberculosis and HIV have synergistic influence on immunity system which may contribute to change in prevalence or severity of CNS involvement in patients with HIV-active TB co infection. Objectives: To study neurological manifestations in patients with HIV-active tuberculosis.

Highlights

At least one-third of the 35.3 million people living migration has been steady and high
Tuberculosis is the most common presenting illness among disaster with far reaching implications for individual people living with HIV, including those who are taking communities and countries
AIDS was tuberculosis, tuberculosis and HIV have synergistic first discovered in June 1981

Summary

Introduction

At least one-third of the 35.3 million people living migration has been steady and high. Tuberculosis is the most common presenting illness among disaster with far reaching implications for individual people living with HIV, including those who are taking communities and countries. Sudan shares extensive borders with nine countries, several of which have high HIV/AIDS prevalence. [5, 6] The neurological complications of AIDS range from acute febrile illness at the time of sero conversion to late onset dementia related to specific brain damage by the virus. HIV may cause damage to the brain causing encephalitis; it may affect the membranes surrounding the brain (meningitis). It may cause difficulties in thinking and behavioral changes. AIDS dementia complex is a well-recognized complication of HIV infection [9]. Peripheral neuropathy, retinitis, myelopathy, demyelination and cerebral space occupying lesions, all can be seen during the course of the disease. [10]

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Conclusion