Abstract
Abstract: Paget’s disease of bone is a chronic focal disorder characterized by disorganized bone remodeling. It is usually asymptomatic and the diagnosis is made incidentally on the basis of other medical problem investigations. Head bones are frequently affected and may cause deformities due to overgrowth of bone leading to neurological manifestations such as headaches, dizziness, and deafness. Here, we describe a case of a 72-year-old woman who complained of headaches, back pain, tinnitus, and hearing loss. Clinical examination showed spinal deformities. Laboratory tests revealed elevated bone remodeling markers. Head computed tomography scan showed bone lesions suggesting Paget’s disease. Isotope bone scan revealed uptake in skull and thoracic spine. The patient was treated with zoledronic acid and analgesic with significant improvement of headaches and back pain and persistence of hearing loss.
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