Abstract
The neurologic complications of Paget's disease are infrequent but can be severe and are often treatable. Paget's disease should be considered as a posible cause of neurologic symptoms, including those with previously undiagnosed disease. Routine neurological assessments should be performed at regular intervals in patients with known Paget's disease of the spine or cranium. The outcome of treatment, particularly in cases of spinal cord compression or hydrocephalus, are particularly rewarding. Treatment should be based on each individual patient's presentation and consists of symptomatic treatment, antiresorptive therapy, or surgery. The latter can frequently be avoided in patients with slow onset spinal cord compression in whom the acute and long-term response to bisphosphonates is impressive.
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