Abstract

Coronavirus disease 2019 (COVID 19) is a catastrophic illness that has significantly altered the world’s panoramic view of medicine. As the number of cases around the globe rise, the COVID-19 research writing has been immediately enhanced by professionals internationally. In this review, we focus on the neurological and psychological effects of COVID-19, which can determine both the severity of coronavirus and its related pandemic respectively. While it is critical to distinguish the neurological manifestations from the psychological effects, the latter is becoming more pervasive due to the fast-expanding outbreak.We conducted a systematic review and included observational retrospective, case-series studies, and surveys to establish the largest pool of valuable research. Articles on these approaches were conducted in PubMed, MEDLINE, and Google scholar. Some gray material was also selected because of the recent nature of the disease.Data collected from the studies have proposed that COVID-19 is not unusual in demonstrating the neurological symptoms, as it proved in the past by its sister coronaviruses such as severe acute respiratory syndrome coronavirus-1 (SARS-COV-1) and Middle Eastern respiratory syndrome coronavirus (MERS-COV). Studies have presented that some patients with COVID-19 also showed neurological signs, such as headache, nausea, vomiting, dizziness, loss of taste and smell, and impaired consciousness. However, it necessary to clarify that the invasion of severe acute respiratory syndrome coronavirus-2 (SARS-COV-2) directly or indirectly affects the central nervous system (CNS).Contrarily, the COVID-19 pandemic has affected every single element of life. It has not only changed the individual’s health directly but also has significant psychological, economic, and sociological effects. These issues indicate the disease's extraordinary threat, and we must realize that another pandemic will shortly follow it: that of mental and behavioral illness. Thus, the long-lasting psychological implications of this outbreak deserve further investigation side by side.

Highlights

  • As coronavirus disease 2019 (COVID-19), and the fears that accompany it, continues to spread around the world, the overall mortality appears to mirror that of pandemic flu [1]

  • COVID-19 has been shown to be a separate group from the previous coronaviruses of the last two decades associated with human SARS and MERS through genomic sequencing and evolutionary differentiation analysis [2]

  • The research mostly pertained to coronavirus effects on the central nervous system (CNS) and mental health issues that developed in communities after the outbreak of COVID-19

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Summary

Introduction

As coronavirus disease 2019 (COVID-19), and the fears that accompany it, continues to spread around the world, the overall mortality appears to mirror that of pandemic flu [1]. The first instances of an acute respiratory illness, known as novel coronavirus-infected pneumonia (NCIP), arose in Wuhan, Hubei. The percentage of people estimated to have symptoms of this disease when combined with likely infection rates could be as much as 50-80% of the worldwide population [4]. The current death rate of the disease is approximately 3-4% [5]. This novel strain of coronavirus is assumed to have possibly originated in bats before being passed to humans, potentially through another animal, such as a pangolin (scaly anteater). Experts believe that similar new viruses will continue to arise from such places as long as they remain in business [6]

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