Abstract

The occurrence of chronic neurologic sequelae including late seizures or epilepsy was determined in a nine year follow-up study of 185 infants and children with bacterial meningitis at the Departments of Pediatrics and Neurology, Washington University School of Medicine, St. Louis, MO and the Department of Pediatrics, Baylor College of Medicine, Houston, TX.

Highlights

  • Seizures occurred in 58 patients (31%) during the acute phase of bacterial meningitis

  • The occurrence of seizures during acute meningitis was strongly associated with the development of late seizures

  • Children with persistent neurologic deficits from bacterial meningitis are at risk for epilepsy whereas those with a normal neurologic examination at time of discharge usually escape neurologic sequelae including epilepsy

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Summary

Introduction

NEUROLOGIC SEQUELAE OF BACTERIAL MENINGITIS The occurrence oT chronic neurologic sequelae including late seizures or epilepsy was determined in a nine year follow-up study of 185 infants and children with bacterial meningitis at the Departments of Pediatrics and Neurology, Washington University School of Medicine, St. Louis, MD and the Department of Pediatrics, Baylor College of Medicine, Houston, TX. Seizures occurred in 58 patients (31%) during the acute phase of bacterial meningitis. Neurologic abnormalities developing during the acute illness had persisted at one month followup in 69 (37%) but many of these signs resolved within a one year period.

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