Neuroimaging on Brain Structural and Functional Abnormality of Borderline Personality Disorder

Abstract

This article is a comprehensive review of borderline personality disorder (BPD) based on the neuroimaging technique. The paper incorporated the etiology of BPD, the correlated brain structure and function abnormality of BPD found by neuroimaging techniques, influence of brain abnormality and recommendations for future research directions. The method used in the paper is to generalise results from pre-existing research and studies by reviewing the literature. The results and discussion section will focus on the comparison between BPD and non-BPD subjects, intending to highlight the most significant anatomical and functional abnormalities in the brain such as the hippocampus, the amygdala and the primary visual processing area. Furthermore, the impact of early trauma, and the connection between brain abnormalities and emotional dysregulation will be discussed in the paper. The suggestions and discussions section at the end will cover the current limitation of BPD neuroimaging research based on the selection bias on gender and provide directions for future research. The overall goal of the current study is to increase knowledge about BPD.