Abstract
Dementia with Lewy bodies (DLB) is one of the most common forms of dementia. It can present as neurocognitive decline, visual hallucinations, and concomitant symptoms of rapid eye movement (REM) sleep behavior disorder. Early diagnosis remains one of the cornerstones of managing this form of neurocognitive disorder but, often, making an early and accurate diagnosis can prove to be challenging. For this article, our goal was to review the utility of various neuroimaging modalities in making a swift and accurate diagnosis of DLB. We used PubMed to look for helpful, informative, and peer-reviewed articles. We discussed the role of a plethora of different imaging techniques, ranging from structural imaging like computed tomography (CT) and magnetic resonance imaging (MRI) to molecular imaging (single-photon emission computed tomography, positron emission to- tomography) as a diagnostic tool for DLB. We arrived at the conclusion that these novel neuroimaging modalities have already proven to be very helpful in ruling out differentials and making an early diagnosis of DLB. However, ongoing research is required to increase the diagnostic accuracy, leading to the early identification and treatment of DLB.
Highlights
Background"The disease might hide the person underneath, but there is still a person underneath who needs your love and attention" - Jamie Calandriello.Review began 05/12/2021 Review ended 06/07/2021 Published 06/16/2021There are almost around 850,000 people with dementia in the United Kingdom
Neuroimaging plays an integral role in the identification of these biomarkers and in this article, we aim to provide a brief review of imaging modalities contributing towards early diagnosis of Dementia with Lewy bodies (DLB)
Alzheimer’s disease (AD) is characterized by more pronounced atrophy in the temporal lobe, amygdala, and hippocampus, which is relatively spared in DLB
Summary
Background"The disease might hide the person underneath, but there is still a person underneath who needs your love and attention" - Jamie Calandriello.Review began 05/12/2021 Review ended 06/07/2021 Published 06/16/2021There are almost around 850,000 people with dementia in the United Kingdom. Dementia with Lewy bodies (DLB) is one of the most common causes of dementia or neurodegenerative disorders, only second to Alzheimer’s disease (AD) [2]. Doctors and scientists across the globe agree that once such treatments are available, patients would most likely benefit from the initiation of treatment as early as possible, which makes early diagnosis of DLB a crucial factor [3]. The most crucial hurdle to overcome in the management of DLB lies in making an early diagnosis and accurately ruling out other possible differentials [5]. Neuroimaging plays an integral role in the identification of these biomarkers and in this article, we aim to provide a brief review of imaging modalities contributing towards early diagnosis of DLB
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
