Abstract
Neurofunctional Abnormalities during Sustained Attention in Severe Childhood Abuse
Highlights
There is increasing interest in understanding the effects of childhood adversities on the developing brain, given evidence that early environmental factors can have a substantial influencePLOS ONE | DOI:10.1371/journal.pone.0165547 November 10, 2016Sustained Attention and Childhood Abuse
This study investigated the association between severe childhood abuse and functional magnetic resonance imaging (fMRI) brain activation during a parametric sustained attention task with a progressively increasing load of sustained attention in 21 medicationnaïve, drug-free young people with a history of childhood abuse controlling for psychiatric comorbidities by including 19 psychiatric controls matched for psychiatric diagnoses, and 27 healthy controls
The findings represent a first step towards the delineation of abuse-related neurofunctional abnormalities in sustained attention, which may help in the development of effective treatments for victims of childhood abuse
Summary
The aim of this study was to test the hypothesis that medication-naïve, drug-free young people with a documented history of childhood physical abuse would exhibit activation deficits during sustained attention
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