Abstract
As indicated by immunofluorescence with neurofilament antiserum and by electron microscopy two neuroblastoma clones in suspension culture contained a pool of neurofilament subunits which could be induced to assemble into filaments following exposure to vinblastine and colchicine. Under the same culture conditions neuroblastoma cells treated with aluminum extended thick processes with many filaments. The processes were much smaller in nontreated cells but still contained bundles of filaments. These filaments persisted after inhibition of protein synthesis by cycloheximide. In the long neurites formed by cells attached to plastic immunofluorescence with neurofilament antiserum was particularly intense at the growth cone.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
