Abstract
It is known that neurofibromatosis 1 is associated with lower IQ in affected individuals than in their unaffected relatives. This disorder once was thought to be a model for Rourke's syndrome of nonverbal learning disabilities, but recent research has revealed that the cognitive phenotype is broader, encompassing verbal, linguistic, and reading impairments. Visuospatial deficit has been confirmed as part of the NF1-associated phenotype, but does not appear to lead to mechanical arithmetic or social failure as Rourke would predict. The reading disability found with NF1 occurs within a developmental language disorder, a context commonly encountered clinically but rarely accounted for by research. Because magnetic resonance imaging yields subcortical rather than cortical findings on children with NF1, this neurogenetic syndrome draws attention to the linguistic contributions of basal ganglia and cerebellum. © 1996 Wiley-Liss, Inc.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Mental Retardation and Developmental Disabilities Research Reviews
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
