Abstract

Four cases of neurofibromatosis complicated by intracranial tumors are reported. Case 1 showed an intracranial neurofibromatosis while the other three cases contained gliomas in various stages of malignancy.Japanese autopsy records for 11 years from 1958 to 1968 were investigated from a statistical point of view. Meningiomas and neurinomas associated with neurofibromatosis show an earlier peak of age distribution than that of those tumors without neurofibromatosis. There is no different age distribution between gliomas related to neurofibromatosis and the ones not related to it.These facts suggest that both neurinomas and meningiomas associated with neurofibromatosis are intracranial manifestations of neurofibromatosis perse, while complicated gliomas are thought to be an incidental neoplasm, probably associated with transformation of disoriented neuroglial rests.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.