Abstract

Neurofeedback Intervention for Emotional Behavior Regulation in Schizophrenia: New Experimental Evidences from Optical Imaging

Highlights

  • Schizophrenia (SZ) is a chronic and severe neuropsychiatric syndrome that affects reasoning, feelings, and behaviors, with a substantial social and relational dysfunction

  • The present research aimed at investigating the effects related to a NF training over the prefrontal neural activity in a small sample of SZ patients

  • The experiment was subdivided into three different sections, with the neurophysiological assessment being proposed at T0 and T2, and the NF training administered in between (T1) and only to the experimental (E) group

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Summary

Introduction

Schizophrenia (SZ) is a chronic and severe neuropsychiatric syndrome that affects reasoning, feelings, and behaviors, with a substantial social and relational dysfunction. Researchers from the neuroscientific field tried to identify some biological markers and neural correlates which could represent the symptoms underlying SZ deficits and support the diagnosis (Linden & Fallgatter, 2009) that is usually made by observable symptoms. Such research engaged patients in different experimental protocols and recorded their neural activity by using different neuroimaging techniques like functional magnetic resonance imaging (fMRI), positron emission tomography (PET), and, more recently, functional near-infrared spectroscopy (fNIRS). Compared to other functional neuroimaging techniques, fNIRS has some disadvantages, such as a lower spatial resolution and the inability to reach deep brain regions. It was successfully applied in studies involving neuropsychiatric patients, since it is portable and can be and noninvasively positioned in naturalistic environments

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