Neuroendocrine Regulation of Food Intake During Acute Stress in the Tilapia

Abstract

Event Abstract Back to Event Neuroendocrine Regulation of Food Intake During Acute Stress in the Tilapia Larry Riley1* and Kelli Upton1 1 California State University at Fresno, Biology, United States The general stress response principally results in the release of cortisol, with the overall effect of mobilizing metabolic energy and redirecting it towards homeostatic maintenance. Consequently, an important factor by stress is food intake. In several teleosts species, a decrease in food intake following stress has been observed, though the neuroendocrine mechanism controlling the reduction in food intake during stress has yet to be determined. These studies were designed to investigate the effect of an acute stress on food intake and brian expression of corticotropin-releasing hormone (CRH), neuropeptide Y (NPY), and ghrelin and whether these effects are mediated cortisol. Therefore, metyrapone, a cortisol synthesis inhibitor, was administered via feed in three doses of 10,25, and 50 mg/kg body weight for 1 wk prior to a 30 min crowding and handling stress. Following the stressor, fish were allowed to feed for 1 h. Stress reduced food intake, while elevating mRNA levels of CRH, an appetite suppressor. Additionally, metyrapone treatment dose-dependently blocked the stress-reduction in food intake. The elevation of CRH mRNA levels was also reveresed with metyrapone treatment, suggesting cortisol and CRH play a role in mediating reduction of food intake during stress in tilapia Acknowledgements This project was supported by Agriculture and Food Research Initiative Competitive Grant no. 2010-65206-20615 from the USDA National Institute of Food and Agriculture to LGR. Keywords: Corticotropin-Releasing Hormone, food intake, Neuropeptide Y, stress, Tilapia Conference: NASCE 2011: The inaugural meeting of the North American Society for Comparative Endocrinology, Ann Arbor, United States, 13 Jul - 16 Jul, 2011. Presentation Type: Poster Topic: Metabolism and feeding Citation: Riley L and Upton K (2011). Neuroendocrine Regulation of Food Intake During Acute Stress in the Tilapia. Front. Endocrinol. Conference Abstract: NASCE 2011: The inaugural meeting of the North American Society for Comparative Endocrinology. doi: 10.3389/conf.fendo.2011.04.00075 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 22 Jul 2011; Published Online: 09 Aug 2011. * Correspondence: Prof. Larry Riley, California State University at Fresno, Biology, Fresno, CA, 93740, United States, lriley@csufresno.edu Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Larry Riley Kelli Upton Google Larry Riley Kelli Upton Google Scholar Larry Riley Kelli Upton PubMed Larry Riley Kelli Upton Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.