Abstract

Multiple endocrine changes are associated with anorexia nervosa and less so with bulimia nervosa. Starvation and malnutrition have been shown to account for virtually all changes on endocrine regulatory control and in the alteration in hormonal metabolic pathways. No one endocrine disturbance can currently be considered pathognomonic for either anorexia nervosa or bulimia nervosa. As long as any nutritional or weight disturbances exist, neither the TRH test nor the Dexamethasone Suppression Test can be used to distinguish eating disorders from major depressive disorders. With treatment, refeeding, and adequate nutrition, endocrine abnormalities normalize.

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