Abstract

Premature infants with a diagnosis of ROP are at a high risk for developing NDDs, even when the visual outcomes are normal. The association of NDDs in ROP may have a common etiological basis, such as damage to the vascular and neuronal pathways during maturation. Our findings underscore the importance of ophthalmological and neurological follow-up and to undertake studies to explore the etiological basis for poor neurological and visual outcomes.

Highlights

  • Infants diagnosed as retinopathy of prematurity (ROP)in the neonatal period remain at high risk for long-term visual disabilities requiring regular screening and timely treatment

  • Premature infants with a diagnosis of ROP are at a high risk for developing neurodevelopmental disabilities (NDD), even when the visual outcomes are normal

  • The early eye health screening and treatment of premature infants are lacking in low and middle-income countries (LMICs) due to poor socioeconomic conditions and lack of public awareness, which is similar to the reports of Vartanian [7] even in high-income countries such as US

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Summary

Introduction

Infants diagnosed as retinopathy of prematurity (ROP)in the neonatal period remain at high risk for long-term visual disabilities requiring regular screening and timely treatment. Infants diagnosed as retinopathy of prematurity (ROP). With the global improvement in neonatal care the survival rate of premature infants is increasing, so in India. According to global report of 2008 [2], ROP is highly prevalent in all high, as well as in low and middle-income countries (LMICs) such as India and south. Blencowe [3] estimated that during the years 2000-2009 nearly 20,000-30,000 children who developed ROP became blind or severe visually impaired worldwide. ROP in premature infants is known to develop both visual impairment and neurodevelopmental. The rates and prevalence of neurodevelopmental disabilities (NDD) among infants and children with a neonatal diagnosis ROP are not well known, in low, and middle-income countries (LMIC). The center evaluates and treats nearly 400 children with ROP annually and has a program for long-term follow up for visual outcome and rehabilitation

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