Neurodevelopment outcomes in ROP patients are similar in standard versus revised oxygen saturation protocols

Abstract

Retinopathy of prematurity (ROP) is a leading cause of childhood blindness in the US. Compared to standard high oxygen saturation targets (>95%), revised protocols using early low targets (85%-92% before 34 weeks gestational age) and late high targets (92-97% after 34 weeks gestations age), to mimic in utero conditions, induces normal retinal development while decreasing the severity and incidence of ROP. Long-term neurodevelopmental outcomes are needed to support the beneficial effect that this revised oxygen saturation protocol has on the retina.