Abstract
Neuroblastoma is a common malignancy of infancy and early childhood. The difference in the outcomes for patients with these neoplasms is striking. Infants younger than one year have a good prognosis, even in the presence of metastatic disease, whereas older patients with metastatic disease fare poorly even when treated with aggressive therapy. The noninvasive nature of diagnostic sonography has allowed it to play a major role in the early detection and treatment of neuroblastoma. This early sonographic detection, in conjunction with early postnatal surgical intervention, has greatly improved the prognosis of infants born with neuroblastoma.
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