Abstract
Neurobehavioral biochemical changes associated with acute administration of omega-3 in male rats
Highlights
The aim of the study is to determine the toxic effect of omega-3 on the neurobehavioral and motor activity in the open field in male rats after 2 and 24 hr of treatment with 2000, 4000, 6000 mg/kg
In swimming test there was a significant decrease in score of swimming, while there was no significant difference in tonic immobility test after 2, 24 hr. there was no significant effect on all neurobehavioral tests by the dose 2000 mg/Kg the only significant decrease was noticed in number of head entrance in holes after 2 and 24 hr
Omega-3 at doses 4000 and 6000 mg/Kg did not produce a significant changes for serum GSH, MDA, TG, and glucose, compared with the control group
Summary
The aim of the study is to determine the toxic effect of omega-3 on the neurobehavioral and motor activity in the open field in male rats after 2 and 24 hr of treatment with 2000, 4000, 6000 mg/kg.
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