Abstract

Neuro‐vascular coupling is a physiological key feature of neural tissues to adapt its blood flow to local metabolic demands. It has been shown that also in the human retina neurons, glia cells and blood vessels are closely coupled. As such, increased retinal neural activity, induced for example by visual stimulation, leads to an immediate increase in blood flow in the optic nerve head as well as in the retinal vasculature.Because of its optical properties and its easy accessibility, the eye offers a unique possibility to non‐invasively investigate neuro‐vascular coupling in humans. The current talk aims to summarize how the role of neuro‐vascular coupling and its potential applications in the diagnosis and follow up in systemic and ocular diseases.

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