Abstract
Neuroimmunophysiology involves direct communication between the mucosal immune system and the minibrain in the colon. Communication is chemical in nature (paracrine) and involves specialized sensing functions of the immune cells for specific antigens together with intelligent interpretation of the signals by the enteric nervous system. Immunoneural integration progresses sequentially starting with immune detection followed by signal transfer to enteric microcircuits followed by neural interpretation and then selection of a specific neural program of coordinated mucosal secretion and motor propulsion that acts to clear the antigenic threat from the colonic lumen. Histamine and serotonin are important chemical messages released from mucosal mast cells to act at specific receptor subtypes on neural elements of the enteric minibrain.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
